Translational genomics of nasopharyngeal cancer

Translational genomics

The term "Translational Genomics" reflects both title and mission of this new journal. "Translational" has traditionally been understood as "applied research" or "development", different from or even opposed to "basic research". Recent scientific and societal developments have triggered a re-assessment of the connotation that "translational" and "basic" are either/or activities: translational r...

Functional genomics in translational cancer research: focus on breast cancer.

Conventional molecular and genetic methods for studying cancer are limited to the analysis of one locus at a time. A cluster of genes that are regulated together can be identified by DNA microarray, and the functional relationships can uncover new aspects of cancer biology. Breast cancer can be used to provide a model to demonstrate the current approaches to the molecular analysis of cancer. Me...

Translational genomics of Vegetable Crops

Translational genomics and head and neck cancer: toward precision medicine.

Head and neck squamous cell carcinoma (HNSCC) comprise a wide spectrum of neoplasms with different tumor biologies, prognosis and response to therapies. Current tumor classification and traditional diagnostic methods (e.g. clinical assessment, histopathology) are limited in their capacity to determine prognosis and clinical decision-making. Despite recent improvements in treatment, the outcome ...

Frontiers in Integrative Genomics and Translational Bioinformatics

1Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37203, USA 2Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN 37212, USA 3Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA 4Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, Sa...